The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 154: Protein disulfide-isomerase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
|
11 |
A2QFJ8 (/IDA)
A2QFJ8 (/IDA)
A2QFJ8 (/IDA)
P17967 (/IDA)
P17967 (/IDA)
P32474 (/IDA)
P32474 (/IDA)
Q4WH99 (/IDA)
Q4WH99 (/IDA)
Q4WH99 (/IDA)
(1 more) |
|
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
|
4 | P17967 (/IMP) P17967 (/IMP) P32474 (/IMP) P32474 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P17967 (/IPI) P17967 (/IPI) P32474 (/IPI) P32474 (/IPI) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
4 | P17967 (/IDA) P17967 (/IDA) P32474 (/IDA) P32474 (/IDA) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
4 | P17967 (/IDA) P17967 (/IDA) P32474 (/IDA) P32474 (/IDA) |
|
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
|
2 | P32474 (/IGI) P32474 (/IGI) |
|
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
|
2 | P32474 (/ISS) P32474 (/ISS) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
2 | P32474 (/IGI) P32474 (/IGI) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
2 | P32474 (/ISS) P32474 (/ISS) |
|
Protein-disulfide reductase (glutathione) activity GO:0019153
Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.
|
2 | P32474 (/IDA) P32474 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
3 | A2QFJ8 (/IDA) A2QFJ8 (/IDA) A2QFJ8 (/IDA) |
|
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
2 | P32474 (/IGI) P32474 (/IGI) |
|
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
2 | P17967 (/IMP) P17967 (/IMP) |
|
Protein alpha-1,2-demannosylation GO:0036508
The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.
|
2 | P17967 (/IDA) P17967 (/IDA) |
|
Mannose trimming involved in glycoprotein ERAD pathway GO:1904382
The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
|
2 | P17967 (/IDA) P17967 (/IDA) |
|
Mannose trimming involved in glycoprotein ERAD pathway GO:1904382
The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
|
2 | P17967 (/IGI) P17967 (/IGI) |
|
Mannose trimming involved in glycoprotein ERAD pathway GO:1904382
The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
|
2 | P17967 (/IMP) P17967 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | P17967 (/HDA) P17967 (/HDA) P32474 (/HDA) P32474 (/HDA) |
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
2 | P17967 (/IDA) P17967 (/IDA) |
