The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 148: Elongation factor 1B gamma

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
8 Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS)
Glutathione transferase activity GO:0004364
Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
8 Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
2 Q382L7 (/ISM) Q382M7 (/ISM)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Glutathione binding GO:0043295
Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
2 Q4WR90 (/IDA) Q4WR90 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
8 Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS)
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
2 Q382L7 (/ISM) Q382M7 (/ISM)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
2 Q9FVT2 (/IEP) Q9FVT2 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9FVT2 (/IEP) Q9FVT2 (/IEP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eukaryotic translation elongation factor 1 complex GO:0005853
A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
8 Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS) Q8IDV0 (/ISS)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
5 O04487 (/IDA) O04487 (/IDA) O04487 (/IDA) Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O04487 (/IDA) O04487 (/IDA) O04487 (/IDA) Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 O04487 (/IDA) O04487 (/IDA) O04487 (/IDA) Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
5 O04487 (/IDA) O04487 (/IDA) O04487 (/IDA) Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
2 Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q9FVT2 (/IDA) Q9FVT2 (/IDA)
Eukaryotic translation elongation factor 1 complex GO:0005853
A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
1 Q382L7 (/ISA)
Eukaryotic translation elongation factor 1 complex GO:0005853
A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
1 Q382M7 (/ISM)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 B0G141 (/HDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 B0G141 (/HDA)
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