The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115: protein disulfide-isomerase TMX3 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q96JJ7 (/IPI) Q96JJ7 (/IPI)
Thiol oxidase activity GO:0016972
Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
2 Q96JJ7 (/IDA) Q96JJ7 (/IDA)
Thiol oxidase activity GO:0016972
Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
1 Q8BXZ1 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2 Q96JJ7 (/TAS) Q96JJ7 (/TAS)
Peptidyl-cysteine oxidation GO:0018171
The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.
2 Q96JJ7 (/IDA) Q96JJ7 (/IDA)
Peptidyl-cysteine oxidation GO:0018171
The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.
1 Q8BXZ1 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
3 Q8BXZ1 (/IDA) Q96JJ7 (/IDA) Q96JJ7 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q96JJ7 (/IDA) Q96JJ7 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q96JJ7 (/TAS) Q96JJ7 (/TAS)
Platelet alpha granule membrane GO:0031092
The lipid bilayer surrounding the platelet alpha granule.
2 Q96JJ7 (/TAS) Q96JJ7 (/TAS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q8BXZ1 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q8BXZ1 (/ISO)
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