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CATH Superfamily 3.40.20.10

Severin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Severin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 46: Cofilin/actin-depolymerizing factor like 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
 15 P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP)
(5 more)
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
 15 Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS)
(5 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
 15 P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP)
(5 more)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
 15 Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS)
(5 more)
Actin filament severing GO:0051014
The process in which an actin filament is broken down into smaller filaments.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
Cytoplasmic actin-based contraction involved in cell motility GO:0060327
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
Cytoplasmic actin-based contraction involved in cell motility GO:0060327
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
 15 P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP) P86292 (/IMP)
(5 more)
Cytoplasmic actin-based contraction involved in cell motility GO:0060327
The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
 15 Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS) Q8I467 (/ISS)
(5 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
 30 P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS) P86292 (/ISS)
(20 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
 15 Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA) Q8I467 (/IDA)
(5 more)
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