The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Periplasmic binding protein-like II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 79: Glycine betaine ABC transporter substrate-binding ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
8 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS)
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
8 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS)
Amine binding GO:0043176
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
8 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS)
Carnitine transmembrane transporter activity GO:0015226
Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
4 Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15 P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA) P33362 (/IDA)
(5 more)
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15 P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI) P33362 (/IPI)
(5 more)
Cellular hyperosmotic response GO:0071474
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
15 P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP) P33362 (/IEP)
(5 more)
Amine transport GO:0015837
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS)
Amino-acid betaine transport GO:0015838
The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)
Cellular hyperosmotic salinity response GO:0071475
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
4 Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
15 P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA) P33362 (/RCA)
(5 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
12 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)
(2 more)
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
8 Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS) Q87WH3 (/ISS)
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
4 Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS) Q9HXC4 (/ISS)
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