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CATH Superfamily 3.40.190.10

Periplasmic binding protein-like II

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Periplasmic binding protein-like II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 149: LysR family transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 29 Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA)
(19 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 17 Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA)
(7 more)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
 12 Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA)
(2 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 12 Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA)
(2 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 12 Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI)
(2 more)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
 12 Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA) Q9HTL4 (/IDA)
(2 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 17 Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP) Q88C74 (/EXP)
(7 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
 12 Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP) Q9HTL4 (/EXP)
(2 more)
Positive regulation of lipid biosynthetic process GO:0046889
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
 12 Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP)
(2 more)
Negative regulation of secondary metabolite biosynthetic process GO:1900377
Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.
 12 Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP)
(2 more)
Regulation of response to reactive oxygen species GO:1901031
Any process that modulates the frequency, rate or extent of response to reactive oxygen species.
 12 Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP)
(2 more)
Positive regulation of superoxide dismutase activity GO:1901671
Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.
 12 Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP)
(2 more)
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
 12 Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP) Q9HTL4 (/IMP)
(2 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 29 Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA) Q88C74 (/IDA)
(19 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 12 Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI) Q9HTL4 (/IPI)
(2 more)