The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cytidine Deaminase, domain 2
".
FunFam 44: Apolipoprotein B mRNA editing enzyme catalytic sub...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q8IUX4 (/HDA) Q9UH17 (/HDA) |
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q8IUX4 (/IDA) |
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
|
1 | Q8IUX4 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8IUX4 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q8IUX4 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8IUX4 (/IPI) |
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
1 | Q9UH17 (/IMP) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
4 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9UH17 (/IDA) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
4 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9UH17 (/IDA) |
Negative regulation of single stranded viral RNA replication via double stranded DNA intermediate GO:0045869
Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
|
3 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) |
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
3 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) |
Cytidine deamination GO:0009972
The removal of amino group in the presence of water.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
|
1 | Q8IUX4 (/IDA) |
Base conversion or substitution editing GO:0016553
Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
|
1 | Q8IUX4 (/IDA) |
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
1 | Q8IUX4 (/IDA) |
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | Q8IUX4 (/IDA) |
Negative regulation of viral process GO:0048525
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
|
1 | Q8IUX4 (/IDA) |
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
|
1 | Q8IUX4 (/IDA) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
3 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | B0QYD3 (/IDA) Q9UH17 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
2 | Q694B8 (/ISS) Q694B9 (/ISS) |
Apolipoprotein B mRNA editing enzyme complex GO:0030895
Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
|
1 | Q8IUX4 (/TAS) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
1 | Q8IUX4 (/IDA) |