The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytidine Deaminase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 31: Probable C->U-editing enzyme APOBEC-2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 A0A2R8Q022 (/IPI) D2D565 (/IPI) F8W3Q7 (/IPI) Q5CZQ2 (/IPI)
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
2 Q9WV35 (/IDA) Q9Y235 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9Y235 (/TAS)
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
1 Q9WV35 (/ISO)
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
1 Q9Y235 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9Y235 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9WV35 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
5 Q3SYR3 (/ISS) Q3SYR3 (/ISS) Q694B4 (/ISS) Q694B4 (/ISS) Q9WV35 (/ISS)
Regeneration GO:0031099
The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).
4 A0A2R8Q022 (/IGI) D2D565 (/IGI) F8W3Q7 (/IGI) Q5CZQ2 (/IGI)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
4 A0A2R8Q022 (/IDA) D2D565 (/IDA) F8W3Q7 (/IDA) Q5CZQ2 (/IDA)
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
4 A0A2R8Q022 (/IMP) D2D565 (/IMP) F8W3Q7 (/IMP) Q5CZQ2 (/IMP)
Skeletal muscle organ development GO:0060538
The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.
4 A0A2R8Q022 (/IMP) D2D565 (/IMP) F8W3Q7 (/IMP) Q5CZQ2 (/IMP)
Sensory epithelium regeneration GO:0070654
The regrowth of a sensory epithelium following its loss or destruction.
4 A0A2R8Q022 (/IMP) D2D565 (/IMP) F8W3Q7 (/IMP) Q5CZQ2 (/IMP)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
2 F8W3Q7 (/IMP) Q5CZQ2 (/IMP)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
2 Q9WV35 (/IDA) Q9Y235 (/IDA)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
1 Q9WV35 (/ISO)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q9WV35 (/IMP)
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
1 Q9Y235 (/IDA)
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
1 Q9WV35 (/ISO)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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