The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cytidine Deaminase, domain 2
".
FunFam 29: DNA dC->dU-editing enzyme APOBEC-3G
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
22 |
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
Q694C1 (/ISS)
(12 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | Q8IUX4 (/IPI) Q99J72 (/IPI) Q9HC16 (/IPI) Q9HC16 (/IPI) Q9NRW3 (/IPI) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | Q8IUX4 (/HDA) Q9NRW3 (/HDA) Q9UH17 (/HDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | Q8IUX4 (/IPI) Q9HC16 (/IPI) Q9HC16 (/IPI) |
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
|
2 | Q9HC16 (/TAS) Q9HC16 (/TAS) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q9HC16 (/NAS) Q9HC16 (/NAS) |
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
2 | Q9HC16 (/IDA) Q9HC16 (/IDA) |
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
|
1 | Q8IUX4 (/IDA) |
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
1 | Q9UH17 (/IMP) |
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
1 | Q99J72 (/ISO) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
25 |
P60704 (/ISS)
P60705 (/ISS)
Q694B5 (/ISS)
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
(15 more) |
Cytidine deamination GO:0009972
The removal of amino group in the presence of water.
|
23 |
Q694B5 (/ISS)
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
(13 more) |
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
22 |
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
Q694C1 (/ISS)
(12 more) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
20 |
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
Q694C1 (/ISS)
(10 more) |
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
9 | Q7YR24 (/IDA) Q7YR24 (/IDA) Q7YR25 (/IDA) Q7YR25 (/IDA) Q8IUX4 (/IDA) Q99J72 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) Q9NRW3 (/IDA) |
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
8 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q99J72 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) Q9NRW3 (/IDA) Q9UH17 (/IDA) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
8 | Q7YR23 (/IDA) Q7YR23 (/IDA) Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) Q9UH17 (/IDA) |
Negative regulation of single stranded viral RNA replication via double stranded DNA intermediate GO:0045869
Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
|
7 | Q7YR23 (/IDA) Q7YR23 (/IDA) Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
5 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Cytidine deamination GO:0009972
The removal of amino group in the presence of water.
|
3 | Q9HC16 (/IDA) Q9HC16 (/IDA) Q9NRW3 (/IDA) |
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Negative regulation of viral process GO:0048525
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Base conversion or substitution editing GO:0016553
Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
|
2 | Q9HC16 (/TAS) Q9HC16 (/TAS) |
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
|
2 | Q8IUX4 (/IDA) Q9NRW3 (/IDA) |
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
1 | Q99J72 (/IGI) |
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
1 | Q99J72 (/ISO) |
Base conversion or substitution editing GO:0016553
Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
|
1 | Q8IUX4 (/IDA) |
Regulation of defense response to virus GO:0050688
Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
|
1 | Q99J72 (/IMP) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | Q99J72 (/ISO) |
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
|
1 | Q694B5 (/ISS) |
Regulation of viral life cycle GO:1903900
Any process that modulates the frequency, rate or extent of viral life cycle.
|
1 | Q99J72 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
25 |
P60704 (/ISS)
P60705 (/ISS)
Q694B5 (/ISS)
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
(15 more) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
22 |
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
Q694C1 (/ISS)
(12 more) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
22 |
Q694B6 (/ISS)
Q694B6 (/ISS)
Q694B7 (/ISS)
Q694B7 (/ISS)
Q694B8 (/ISS)
Q694B9 (/ISS)
Q694C0 (/ISS)
Q694C0 (/ISS)
Q694C1 (/ISS)
Q694C1 (/ISS)
(12 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | Q7YR23 (/IDA) Q7YR23 (/IDA) Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q99J72 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) Q9NRW3 (/IDA) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
5 | Q8IUX4 (/IDA) Q96AK3 (/IDA) Q96AK3 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | B0QYD3 (/IDA) Q9NRW3 (/IDA) Q9UH17 (/IDA) |
Apolipoprotein B mRNA editing enzyme complex GO:0030895
Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
|
3 | Q8IUX4 (/TAS) Q9HC16 (/TAS) Q9HC16 (/TAS) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
3 | Q8IUX4 (/IDA) Q9HC16 (/IDA) Q9HC16 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9HC16 (/TAS) Q9HC16 (/TAS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q99J72 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q694B5 (/ISS) |