The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 11: tRNA-splicing endonuclease subunit Sen2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA-intron endonuclease activity GO:0000213
Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
9 P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA)
TRNA-intron endonuclease activity GO:0000213
Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
9 P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI) P16658 (/IPI)
TRNA-intron endonuclease activity GO:0000213
Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
1 Q8TFH7 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA-type intron splice site recognition and cleavage GO:0000379
RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.
9 P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA)
TRNA-type intron splice site recognition and cleavage GO:0000379
RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.
9 P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP)
MRNA cleavage involved in mRNA processing GO:0098787
Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.
9 P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 Q5AF73 (/IMP) Q5AF73 (/IMP)
TRNA-type intron splice site recognition and cleavage GO:0000379
RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.
1 Q8TFH7 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA-intron endonuclease complex GO:0000214
A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
9 P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
9 P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA) P16658 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
9 P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA) P16658 (/IDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
9 P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP) P16658 (/IMP)
TRNA-intron endonuclease complex GO:0000214
A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
1 Q8TFH7 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8TFH7 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 Q8TFH7 (/ISO)