The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RNA polymerase, Rpb5, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: RNA polymerase I subunit 1RPB5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
4 Q388R6 (/ISM) Q388R6 (/ISM) Q388R6 (/ISM) Q388R6 (/ISM)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
4 Q388R6 (/ISM) Q388R6 (/ISM) Q388R6 (/ISM) Q388R6 (/ISM)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q388R6 (/ISA) Q388R6 (/ISA) Q388R6 (/ISA) Q388R6 (/ISA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
4 Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
4 Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA) Q388R6 (/IDA)
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