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CATH Superfamily 3.40.1180.10

Decaprenyl diphosphate synthase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Decaprenyl diphosphate synthase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Isoprenyl transferase 2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(2Z,6E)-farnesyl diphosphate synthase. [EC: 2.5.1.68]
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)- farnesyl diphosphate.
  • The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan.
  • Neryl diphosphate can also act as substrate.
 77 A0A045IN60 A0A045IN60 A0A045IN60 A0A045IN60 A0A045IN60 A0A045IN60 A0A0D6IXM7 A0A0D6IXM7 A0A0D6IXM7 A0A0E7ZYJ3
(67 more...)
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl- diphosphate specific). [EC: 2.5.1.89]
Geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate.
  • This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria.
  • Unlike EC 2.5.1.31, its counterpart in most bacteria, it prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate, resulting in production of a tritrans,polycis variant of undecaprenyl diphosphate.
 7 B0R6C4 B0R6C4 Q58767 Q5JGE1 Q8TJQ7 Q9HP68 Q9HP68
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