The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribosomal protein l15e
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ribosomal protein L15

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
67 O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS)
(57 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
57 P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA)
(47 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
57 P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS)
(47 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
57 P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI) P61313 (/IPI)
(47 more)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
57 P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA)
(47 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
22 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA)
(12 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
14 C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS)
(4 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
13 P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P54780 (/IDA) P54780 (/IDA) P54780 (/IDA) P54780 (/IDA)
(3 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
4 Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
2 O74895 (/ISO) Q9US22 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q86K01 (/ISS)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
1 Q38CY7 (/ISM)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
57 P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS) P61313 (/NAS)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
SRP-dependent cotranslational protein targeting to membrane GO:0006614
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Viral transcription GO:0019083
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
57 P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP) P61314 (/IEP)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
14 C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS)
(4 more)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
13 P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P54780 (/IDA) P54780 (/IDA) P54780 (/IDA) P54780 (/IDA)
(3 more)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
10 O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
7 P54780 (/IMP) P54780 (/IMP) P54780 (/IMP) P54780 (/IMP) P54780 (/IMP) P54780 (/IMP) P54780 (/IMP)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
2 O74895 (/ISO) Q9US22 (/ISO)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
1 Q38CY7 (/ISM)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
79 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA) P05748 (/IDA)
(69 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
66 O74895 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P61313 (/HDA) P61313 (/HDA)
(56 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
59 O74895 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO)
(49 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
57 P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA) P61313 (/IDA)
(47 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
57 Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO)
(47 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Ribosome GO:0005840
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
57 P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS) P61313 (/TAS)
(47 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
57 P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA) P61313 (/HDA)
(47 more)
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
57 P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA) P61314 (/IDA)
(47 more)
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
57 Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO) Q9CZM2 (/ISO)
(47 more)
Ribosome GO:0005840
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
13 C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS) C0H4A6 (/ISS)
(3 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
10 O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS) O17445 (/TAS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
9 O74895 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) Q9US22 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA) P54780 (/HDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
5 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA)
Cytosolic ribosome GO:0022626
A ribosome located in the cytosol.
5 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA)
Polysomal ribosome GO:0042788
A ribosome bound to mRNA that forms part of a polysome.
5 O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA) O23515 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
4 Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA) Q8VYF1 (/IDA)
Ribosome GO:0005840
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
1 Q38CY7 (/ISM)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
1 Q86K01 (/ISS)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 Q86K01 (/HDA)