The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Pyrimidine-nucleoside phosphorylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyrimidine-nucleoside phosphorylase activity GO:0016154
Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.
15 A0A0F7R8Q7 (/ISS) A0A0F7R8Q7 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS)
(5 more)
Thymidine phosphorylase activity GO:0009032
Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
2 P19971 (/IDA) P19971 (/IDA)
Thymidine phosphorylase activity GO:0009032
Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
2 P19971 (/IMP) P19971 (/IMP)
Thymidine phosphorylase activity GO:0009032
Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
2 P47717 (/ISS) P77836 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P19971 (/IDA) P19971 (/IDA)
Phosphorylase activity GO:0004645
Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
1 Q99N42 (/TAS)
Thymidine phosphorylase activity GO:0009032
Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
1 Q99N42 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q99N42 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
15 A0A0F7R8Q7 (/ISS) A0A0F7R8Q7 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS) A0A0J1I223 (/ISS)
(5 more)
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
2 P19971 (/IMP) P19971 (/IMP)
Pyrimidine nucleoside metabolic process GO:0006213
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
2 P19971 (/IDA) P19971 (/IDA)
Pyrimidine nucleoside metabolic process GO:0006213
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
2 P19971 (/IMP) P19971 (/IMP)
Pyrimidine nucleoside metabolic process GO:0006213
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
2 P47717 (/ISS) P77836 (/ISS)
Regulation of myelination GO:0031641
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
2 P19971 (/IMP) P19971 (/IMP)
Pyrimidine nucleoside salvage GO:0043097
Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.
2 P19971 (/TAS) P19971 (/TAS)
Pyrimidine nucleoside catabolic process GO:0046135
The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
2 P19971 (/TAS) P19971 (/TAS)
Regulation of transmission of nerve impulse GO:0051969
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
2 P19971 (/IMP) P19971 (/IMP)
Regulation of gastric motility GO:1905333
Any process that modulates the frequency, rate or extent of gastric motility.
2 P19971 (/IMP) P19971 (/IMP)
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
1 Q99N42 (/ISO)
Pyrimidine nucleoside metabolic process GO:0006213
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
1 Q99N42 (/ISO)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 Q99N42 (/TAS)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 Q99N42 (/TAS)
Regulation of myelination GO:0031641
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
1 Q99N42 (/ISO)
Regulation of transmission of nerve impulse GO:0051969
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
1 Q99N42 (/ISO)
Regulation of gastric motility GO:1905333
Any process that modulates the frequency, rate or extent of gastric motility.
1 Q99N42 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P19971 (/TAS) P19971 (/TAS)
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