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CATH Superfamily 3.40.1010.10

Tetrapyrrole methylase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cobalt-precorrin-4 Transmethylase; Domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Ribosomal RNA small subunit methyltransferase I

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
16S rRNA (cytidine(1402)-2'-O)-methyltransferase. [EC: 2.1.1.198]
S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA = S-adenosyl-L- homocysteine + 2'-O-methylcytidine(1402) in 16S rRNA.
  • RsmI catalyzes the 2'-O-methylation of cytidine(1402) and RsmH (EC 2.1.1.199) catalyzes the N(4)-methylation of cytidine(1402) in 16S rRNA.
  • Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
 49 A0A0F6AJG3 A0A0F6AJG3 A0A0F6AJG3 A0A0F6AJG3 A0A0F6AJG3 A0A0F6AJG3 A0A0F6AJG3 A0A101ES32 A0A101ES32 A0A101ES32
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