The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Siroheme synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Uroporphyrin-III C-methyltransferase activity GO:0004851
Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.
86 P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA) P0AEA8 (/IDA)
(76 more)
Uroporphyrin-III C-methyltransferase activity GO:0004851
Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.
21 A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS)
(11 more)
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
14 G3XD80 (/IDA) G3XD80 (/IDA) G3XD80 (/IDA) G3XD80 (/IDA) G3XD80 (/IDA) G3XD80 (/IDA) G3XD80 (/IDA) P95417 (/IDA) P95417 (/IDA) P95417 (/IDA)
(4 more)
Uroporphyrinogen-III synthase activity GO:0004852
Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.
1 Q747I0 (/ISS)
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
1 Q5LL08 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
83 P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP) P0AEA8 (/IMP)
(73 more)
Porphyrin-containing compound biosynthetic process GO:0006779
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
20 A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS) A0A1S0QMW4 (/ISS)
(10 more)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
14 G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) P95417 (/IMP) P95417 (/IMP) P95417 (/IMP)
(4 more)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
14 G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) P95417 (/IMP) P95417 (/IMP) P95417 (/IMP)
(4 more)
Coenzyme biosynthetic process GO:0009108
The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
14 G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) G3XD80 (/IMP) P95417 (/IMP) P95417 (/IMP) P95417 (/IMP)
(4 more)
Siroheme biosynthetic process GO:0019354
The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
3 Q42606 (/IDA) Q46BL0 (/IDA) Q46BL0 (/IDA)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
1 Q5LL08 (/ISS)
Denitrification pathway GO:0019333
The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.
1 Q5LL08 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q42606 (/IDA)
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