The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Bira Bifunctional Protein; Domain 2
".
FunFam 36: phenylalanine--tRNA ligase alpha subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phenylalanine-tRNA ligase activity GO:0004826
Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
|
6 | Q1JPX3 (/ISS) Q505J8 (/ISS) Q5RFA2 (/ISS) Q5RFA2 (/ISS) Q7SYV0 (/ISS) Q8C0C7 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q9Y285 (/HDA) Q9Y285 (/HDA) |
|
Phenylalanine-tRNA ligase activity GO:0004826
Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
|
2 | Q9Y285 (/IDA) Q9Y285 (/IDA) |
|
Phenylalanine-tRNA ligase activity GO:0004826
Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
|
2 | Q9Y285 (/TAS) Q9Y285 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9Y285 (/IPI) Q9Y285 (/IPI) |
|
Phenylalanine-tRNA ligase activity GO:0004826
Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
|
1 | Q8C0C7 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phenylalanyl-tRNA aminoacylation GO:0006432
The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
6 | Q1JPX3 (/ISS) Q505J8 (/ISS) Q5RFA2 (/ISS) Q5RFA2 (/ISS) Q7SYV0 (/ISS) Q8C0C7 (/ISS) |
|
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
6 | Q1JPX3 (/ISS) Q505J8 (/ISS) Q5RFA2 (/ISS) Q5RFA2 (/ISS) Q7SYV0 (/ISS) Q8C0C7 (/ISS) |
|
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
|
2 | Q9Y285 (/TAS) Q9Y285 (/TAS) |
|
Phenylalanyl-tRNA aminoacylation GO:0006432
The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
2 | Q9Y285 (/IDA) Q9Y285 (/IDA) |
|
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
2 | Q9Y285 (/IDA) Q9Y285 (/IDA) |
|
Phenylalanyl-tRNA aminoacylation GO:0006432
The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
1 | Q8C0C7 (/ISO) |
|
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
1 | Q8C0C7 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phenylalanine-tRNA ligase complex GO:0009328
An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).
|
6 | Q1JPX3 (/ISS) Q505J8 (/ISS) Q5RFA2 (/ISS) Q5RFA2 (/ISS) Q7SYV0 (/ISS) Q8C0C7 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | Q1JPX3 (/ISS) Q5RFA2 (/ISS) Q5RFA2 (/ISS) Q7SYV0 (/ISS) Q8C0C7 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9Y285 (/TAS) Q9Y285 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9Y285 (/TAS) Q9Y285 (/TAS) |
|
Phenylalanine-tRNA ligase complex GO:0009328
An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).
|
2 | Q9Y285 (/IDA) Q9Y285 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9Y285 (/HDA) Q9Y285 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q505J8 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8C0C7 (/ISO) |
|
Phenylalanine-tRNA ligase complex GO:0009328
An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).
|
1 | Q8C0C7 (/ISO) |
