The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Bira Bifunctional Protein; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 191: Bifunctional protein BirA: biotin operon repressor...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Biotin binding GO:0009374
Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
4 I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA)
Biotin-protein ligase activity GO:0018271
Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.
4 P96884 (/IDA) P96884 (/IDA) P96884 (/IDA) P96884 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Biotin metabolic process GO:0006768
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
4 P96884 (/IDA) P96884 (/IDA) P96884 (/IDA) P96884 (/IDA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA)
Protein biotinylation GO:0009305
The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid.
4 P96884 (/IDA) P96884 (/IDA) P96884 (/IDA) P96884 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
4 I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA) I6YFP0 (/IDA)
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