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CATH Superfamily 3.30.930.10

Bira Bifunctional Protein; Domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Bira Bifunctional Protein; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Glycine--tRNA ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine-tRNA ligase activity GO:0004820
Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
 58 A1TBP9 (/ISS) B2S075 (/ISS) B2S075 (/ISS) B2S3R1 (/ISS) B2S3R1 (/ISS) B2S3R1 (/ISS) B7J1U3 (/ISS) O51344 (/ISS) O83678 (/ISS) O83678 (/ISS)
(48 more)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
 58 A1TBP9 (/ISS) B2S075 (/ISS) B2S075 (/ISS) B2S3R1 (/ISS) B2S3R1 (/ISS) B2S3R1 (/ISS) B7J1U3 (/ISS) O51344 (/ISS) O83678 (/ISS) O83678 (/ISS)
(48 more)
Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity GO:0004081
Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
 20 P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA)
(10 more)
Glycine-tRNA ligase activity GO:0004820
Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
 20 P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA)
(10 more)
Glycine-tRNA ligase activity GO:0004820
Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
 20 P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS)
(10 more)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
 20 P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA)
(10 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
 20 P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS)
(10 more)
Diadenosine tetraphosphate biosynthetic process GO:0015966
The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
 20 P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA)
(10 more)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 20 P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 20 P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA) P9WFV6 (/IDA)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 20 P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS) P9WFV6 (/TAS)
(10 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
 20 P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP)
(10 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
 20 P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS) P9WFV6 (/ISS)
(10 more)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
 20 P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP)
(10 more)
Microvesicle GO:1990742
An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.
 20 P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP) P9WFV6 (/EXP)
(10 more)
Microvesicle GO:1990742
An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.
 20 P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP) P9WFV6 (/IEP)
(10 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 10 P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA) P9WFV7 (/HDA)
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