The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
STAS domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Solute carrier family 26 member 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 26 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Sulfate transmembrane transporter activity GO:0015116
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Anion:anion antiporter activity GO:0015301
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Oxalate transmembrane transporter activity GO:0019531
Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8CIW6 (/IPI)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 Q8CIW6 (/IDA)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 Q8CIW6 (/ISO)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 Q9BXS9 (/ISS)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
1 Q8CIW6 (/IDA)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
1 Q8CIW6 (/ISO)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
1 Q9BXS9 (/ISS)
Sulfate transmembrane transporter activity GO:0015116
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
1 Q8CIW6 (/IDA)
Sulfate transmembrane transporter activity GO:0015116
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
1 Q8CIW6 (/ISO)
Anion:anion antiporter activity GO:0015301
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
1 Q8CIW6 (/IDA)
Anion:anion antiporter activity GO:0015301
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
1 Q8CIW6 (/ISO)
Anion:anion antiporter activity GO:0015301
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
1 Q9BXS9 (/ISS)
Formate transmembrane transporter activity GO:0015499
Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
1 Q8CIW6 (/IDA)
Formate transmembrane transporter activity GO:0015499
Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
1 Q9BXS9 (/ISS)
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
1 Q9BXS9 (/ISS)
Formate efflux transmembrane transporter activity GO:0015660
Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.
1 Q8CIW6 (/IMP)
Formate efflux transmembrane transporter activity GO:0015660
Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.
1 Q9BXS9 (/ISS)
Oxalate transmembrane transporter activity GO:0019531
Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
1 Q8CIW6 (/IDA)
Oxalate transmembrane transporter activity GO:0019531
Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
1 Q8CIW6 (/ISO)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q8CIW6 (/IDA)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q9BXS9 (/ISS)

There are 50 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Oxalate transport GO:0019532
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Transepithelial chloride transport GO:0030321
The directed movement of chloride ions from one side of an epithelium to the other.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
2 Q8CIW6 (/IMP) Q9BXS9 (/IMP)
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9BXS9 (/TAS)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/IDA)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/ISO)
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/IDA)
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/ISO)
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9BXS9 (/ISS)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/IDA)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/ISO)
Formate transport GO:0015724
The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/IDA)
Formate transport GO:0015724
The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8CIW6 (/IMP)
Formate transport GO:0015724
The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9BXS9 (/ISS)
Mannitol transport GO:0015797
The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
1 Q8CIW6 (/IMP)
Mannitol transport GO:0015797
The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
1 Q9BXS9 (/ISS)
Oxalate transport GO:0019532
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
1 Q8CIW6 (/IDA)
Oxalate transport GO:0019532
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
1 Q8CIW6 (/ISO)
Oxalate transport GO:0019532
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
1 Q9BXS9 (/ISS)
Transepithelial chloride transport GO:0030321
The directed movement of chloride ions from one side of an epithelium to the other.
1 Q8CIW6 (/ISO)
Transepithelial chloride transport GO:0030321
The directed movement of chloride ions from one side of an epithelium to the other.
1 Q9BXS9 (/ISS)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
1 Q8CIW6 (/ISO)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
1 Q8CIW6 (/ISS)
Epithelial fluid transport GO:0042045
The directed movement of fluid across epithelia.
1 Q8CIW6 (/IMP)
Epithelial fluid transport GO:0042045
The directed movement of fluid across epithelia.
1 Q9BXS9 (/ISS)
Oxalic acid secretion GO:0046724
The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.
1 Q8CIW6 (/IMP)
Oxalic acid secretion GO:0046724
The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.
1 Q9BXS9 (/ISS)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 Q8CIW6 (/IMP)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 Q9BXS9 (/ISS)
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
1 Q8CIW6 (/IMP)
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
1 Q9BXS9 (/ISS)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 Q8CIW6 (/ISO)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 Q8CIW6 (/ISS)
Intracellular pH elevation GO:0051454
Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 Q8CIW6 (/IMP)
Intracellular pH elevation GO:0051454
Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 Q9BXS9 (/ISS)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 Q8CIW6 (/ISO)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 Q8CIW6 (/ISS)
Transepithelial transport GO:0070633
The directed movement of a substance from one side of an epithelium to the other.
1 Q8CIW6 (/IMP)
Transepithelial transport GO:0070633
The directed movement of a substance from one side of an epithelium to the other.
1 Q9BXS9 (/ISS)
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 Q8CIW6 (/IDA)
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 Q9BXS9 (/ISS)
Cellular response to fructose stimulus GO:0071332
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 Q8CIW6 (/IDA)
Cellular response to fructose stimulus GO:0071332
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 Q9BXS9 (/ISS)
Cellular response to interferon-gamma GO:0071346
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.
1 Q9BXS9 (/IDA)
Cellular response to interferon-gamma GO:0071346
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.
1 Q8CIW6 (/ISO)
Positive regulation of dipeptide transmembrane transport GO:2001150
Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
1 Q8CIW6 (/IMP)
Positive regulation of dipeptide transmembrane transport GO:2001150
Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
1 Q9BXS9 (/ISS)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 Q8CIW6 (/IDA) Q9BXS9 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
2 Q8CIW6 (/IDA) Q9BXS9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8CIW6 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8CIW6 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9BXS9 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8CIW6 (/IDA)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
1 Q8CIW6 (/IDA)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
1 Q9BXS9 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8CIW6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9BXS9 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9BXS9 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8CIW6 (/ISO)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q9BXS9 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q8CIW6 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 Q8CIW6 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q8CIW6 (/ISO)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q8CIW6 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q9BXS9 (/ISS)
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
1 Q8CIW6 (/IDA)
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
1 Q9BXS9 (/ISS)