The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: ATP-dependent zinc metalloprotease FtsH

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP-dependent peptidase activity GO:0004176
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
120 P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI)
(110 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
120 P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM)
(110 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
120 P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM)
(110 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
CTPase activity GO:0043273
Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
120 P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP) P0AAI3 (/IMP)
(110 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
120 P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM) P0AAI3 (/ISM)
(110 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
120 P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA) P0AAI3 (/IDA)
(110 more)
Membrane protein complex GO:0098796
Any protein complex that is part of a membrane.
120 P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI) P0AAI3 (/IPI)
(110 more)
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