The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Potassium Channel Kv1.1; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Transcription elongation factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
235 P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI) P83940 (/IPI)
(225 more)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
76 P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI) P83941 (/IPI)
(66 more)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
76 P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO)
(66 more)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q9BKS1 (/IPI)
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
1 Q9BKS1 (/IDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
76 P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA)
(66 more)
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
7 Q7JWD6 (/IGI) Q7JWD6 (/IGI) Q7JWD6 (/IGI) Q7JWD6 (/IGI) Q7JWD6 (/IGI) Q7JWD6 (/IGI) Q7KYI0 (/IGI)
Negative regulation of receptor signaling pathway via JAK-STAT GO:0046426
Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.
6 Q7JWD6 (/IMP) Q7JWD6 (/IMP) Q7JWD6 (/IMP) Q7JWD6 (/IMP) Q7JWD6 (/IMP) Q7JWD6 (/IMP)
Anterior/posterior axis specification, embryo GO:0008595
The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
1 Q9BKS1 (/IMP)
Sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation GO:0051759
The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.
1 Q9BKS1 (/IMP)
Positive regulation of metaphase/anaphase transition of meiotic cell cycle GO:1902104
Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
1 Q9BKS1 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Elongin complex GO:0070449
A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (abut 100 kDa)and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa)subunits.
83 P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA) P83940 (/IDA)
(73 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
76 Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS) Q15369 (/TAS)
(66 more)
VCB complex GO:0030891
A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
76 P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA) P83941 (/IDA)
(66 more)
VCB complex GO:0030891
A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
76 P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO) P83940 (/ISO)
(66 more)
Cul2-RING ubiquitin ligase complex GO:0031462
A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
8 Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7KYI0 (/IDA) Q9BKS1 (/IDA)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
7 Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7KYI0 (/IDA)
Polytene chromosome interband GO:0005705
A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.
7 Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7JWD6 (/IDA) Q7KYI0 (/IDA)
Cul2-RING ubiquitin ligase complex GO:0031462
A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
1 Q9BKS1 (/IPI)
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