The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SEA domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Mucin glycoprotein MUC3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O35419 (/IPI) Q685J3 (/IPI)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q685J3 (/IPI)
Extracellular matrix constituent, lubricant activity GO:0030197
Functions as a lubricant for an extracellular matrix, such as a mucous membrane.
1 Q685J3 (/HDA)
Extracellular matrix constituent, lubricant activity GO:0030197
Functions as a lubricant for an extracellular matrix, such as a mucous membrane.
1 Q685J3 (/NAS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Stimulatory C-type lectin receptor signaling pathway GO:0002223
Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.
2 Q685J3 (/TAS) Q9H195 (/TAS)
O-glycan processing GO:0016266
The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.
2 Q685J3 (/TAS) Q9H195 (/TAS)
Cellular homeostasis GO:0019725
Any process involved in the maintenance of an internal steady state at the level of the cell.
2 O35419 (/TAS) Q685J3 (/TAS)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
6 E9PWP7 (/IDA) O35419 (/IDA) Q685J3 (/IDA) Q80Y91 (/IDA) Q8R0K3 (/IDA) Q91WF4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 E9PWP7 (/ISO) O35419 (/ISO) Q80Y91 (/ISO) Q8R0K3 (/ISO) Q91WF4 (/ISO)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
5 E9PWP7 (/IDA) O35419 (/IDA) Q80Y91 (/IDA) Q8R0K3 (/IDA) Q91WF4 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
5 E9PWP7 (/ISO) O35419 (/ISO) Q80Y91 (/ISO) Q8R0K3 (/ISO) Q91WF4 (/ISO)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
2 Q685J3 (/TAS) Q9H195 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q685J3 (/TAS) Q9H195 (/TAS)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 Q685J3 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 O35419 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 Q685J3 (/HDA)