The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Peptidase S8, pro-domain
".
FunFam 1: Proprotein convertase subtilisin/kexin type 5
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Furin.
[EC: 3.4.21.75]
Release of mature proteins from their proproteins by cleavage of -Arg- Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors.
|
11 |
A0A024RC70
A0A024RC70
P09958
P09958
P23188
P23377
P26016
P29119
P30430
P30432 (1 more...) |
|
Proprotein convertase 1.
[EC: 3.4.21.93]
Release of protein hormones, neuropeptides and renin from their precursors, generally by hydrolysis of -Lys-Arg-|- bonds.
|
8 | P28840 P29120 P63239 P63239 P63240 Q32MU0 Q32MU0 Q9GLR1 |
