The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Poly(A) polymerase predicted RNA binding domain
".
FunFam 3: Poly(A) polymerase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
7 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) Q9UW26 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) Q10295 (/IPI) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
6 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
6 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) |
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
2 | O42617 (/ISS) Q9UW26 (/ISS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9UW26 (/IDA) |
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
1 | Q10295 (/IGI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
7 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) Q9UW26 (/IDA) |
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
6 | P29468 (/IMP) P29468 (/IMP) P29468 (/IMP) P29468 (/IMP) P29468 (/IMP) P29468 (/IMP) |
RNA polyadenylation GO:0043631
The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
|
6 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) |
SnoRNA polyadenylation GO:0071050
The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA molecule. In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.
|
6 | P29468 (/IGI) P29468 (/IGI) P29468 (/IGI) P29468 (/IGI) P29468 (/IGI) P29468 (/IGI) |
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
|
2 | O42617 (/IMP) Q9UW26 (/IMP) |
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
1 | Q10295 (/IGI) |
Nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts GO:0033621
The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
|
1 | Q10295 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) P29468 (/IPI) |
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
|
6 | P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) P29468 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10295 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10295 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q10295 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q10295 (/IDA) |
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
|
1 | Q10295 (/IGI) |
Mmi1 nuclear focus GO:1990251
A protein complex that forms during vegetative growth and is involved in the selective degradation of meiosis-specific transcripts. Contains at least Mmi1, or an ortholog of it.
|
1 | Q10295 (/IDA) |