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CATH Superfamily 3.30.70.590

Poly(A) polymerase predicted RNA binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Poly(A) polymerase predicted RNA binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Nuclear poly(A) polymerase 4

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Polynucleotide adenylyltransferase. [EC: 2.7.7.19]
ATP + RNA(n) = diphosphate + RNA(n+1).
  • Also acts slowly with CTP.
  • Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • The primer, depending on the source of the enzyme, may be an RNA or DNA fragment or oligo(A) bearing a 3'-OH terminal group.
  • See also EC 2.7.7.6.
 9 A0A178VXR1 A0A178VXR1 A0A178W197 A0A178W197 O82312 O82312 Q8VYW1 Q9LMT2 Q9LMT2