The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Poly(A) polymerase predicted RNA binding domain
".
FunFam 1: Putative poly(A) polymerase gamma
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
15 |
A0A0B4KG96 (/IDA)
P25500 (/IDA)
P51003 (/IDA)
P51003 (/IDA)
P51003 (/IDA)
P51003 (/IDA)
P51003 (/IDA)
P51003 (/IDA)
Q61183 (/IDA)
Q8MZ09 (/IDA)
(5 more) |
|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
13 |
A0A0B4KG96 (/ISS)
P51003 (/ISS)
P51003 (/ISS)
P51003 (/ISS)
P51003 (/ISS)
P51003 (/ISS)
P51003 (/ISS)
Q61183 (/ISS)
Q6PCL9 (/ISS)
Q8MZ09 (/ISS)
(3 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | P51003 (/IPI) P51003 (/IPI) P51003 (/IPI) P51003 (/IPI) P51003 (/IPI) P51003 (/IPI) Q61183 (/IPI) Q9WVP6 (/IPI) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
7 | P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) Q61183 (/ISS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
7 | P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) Q61183 (/ISS) |
|
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
|
7 | P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) Q61183 (/ISS) |
|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
|
3 | Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) |
|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
2 | Q61183 (/ISO) Q6PCL9 (/ISO) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | P25500 (/IDA) |
|
Polynucleotide adenylyltransferase activity GO:0004652
Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
|
1 | Q9WVP6 (/ISA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | P25500 (/IDA) |
|
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
|
1 | P25500 (/IDA) |
|
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
|
1 | Q6PCL9 (/ISO) |
|
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
|
1 | Q6PCL9 (/ISS) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polyadenylation GO:0043631
The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
|
8 | P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) P51003 (/ISS) Q61183 (/ISS) Q6PCL9 (/ISS) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
6 | P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) |
|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
6 | A0A0B4KG96 (/ISS) P25500 (/ISS) Q61183 (/ISS) Q8MZ09 (/ISS) Q9N6D7 (/ISS) Q9NDU1 (/ISS) |
|
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
|
6 | P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) P51003 (/IDA) |
|
RNA polyadenylation GO:0043631
The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
|
5 | P25500 (/IDA) Q61183 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) |
|
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
|
2 | P25500 (/ISS) Q61183 (/ISS) |
|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
1 | Q61183 (/ISO) |
|
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
|
1 | Q61183 (/ISO) |
|
RNA polyadenylation GO:0043631
The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
|
1 | Q9WVP6 (/ISA) |
|
RNA polyadenylation GO:0043631
The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
|
1 | Q6PCL9 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
25 |
A0A024R6M3 (/IDA)
A0A024R6M3 (/IDA)
A0A024R6M3 (/IDA)
A0A024R6M3 (/IDA)
A0A024R6M3 (/IDA)
A0A024R6M3 (/IDA)
A0A0C4DH56 (/IDA)
A0A0C4DH56 (/IDA)
G3V2A0 (/IDA)
G3V2A0 (/IDA)
(15 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | A0A0C4DH56 (/IDA) A0A0C4DH56 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9WVP6 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) P51003 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A0C4DH56 (/IDA) A0A0C4DH56 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
5 | A0A0C4DH56 (/IDA) A0A0C4DH56 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) Q9BWT3 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | Q9BWT3 (/HDA) Q9BWT3 (/HDA) Q9BWT3 (/HDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q61183 (/ISO) Q6PCL9 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q6PCL9 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q6PCL9 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9WVP6 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9WVP6 (/IPI) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q6PCL9 (/ISO) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q6PCL9 (/ISO) |
