The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 61: cleavage stimulation factor subunit 2 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | P33240 (/HDA) P33240 (/HDA) P33240 (/HDA) P33240 (/HDA) Q9H0L4 (/HDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) Q8C7E9 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P33240 (/IPI) P33240 (/IPI) P33240 (/IPI) P33240 (/IPI) Q9H0L4 (/IPI) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
2 | Q86NL1 (/ISS) Q9VE52 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q8BIQ5 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
5 | P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) Q9H0L4 (/TAS) |
|
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
|
5 | P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) Q9H0L4 (/TAS) |
|
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
|
5 | P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) Q9H0L4 (/TAS) |
|
TRNA splicing, via endonucleolytic cleavage and ligation GO:0006388
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
|
4 | P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) |
|
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
|
3 | A0A0G2JWP1 (/IEP) A0A0G2K6F9 (/IEP) B4F7F1 (/IEP) |
|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
1 | Q8C7E9 (/TAS) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9VE52 (/IGI) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
9 | E7EWR4 (/IDA) E7EWR4 (/IDA) E7EWR4 (/IDA) E7EWR4 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) Q9H0L4 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
8 | E7EWR4 (/IDA) E7EWR4 (/IDA) E7EWR4 (/IDA) E7EWR4 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
5 | P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) P33240 (/TAS) Q9H0L4 (/TAS) |
|
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
|
4 | P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) |
|
Cleavage body GO:0071920
A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
|
4 | P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) P33240 (/IDA) |
|
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
|
3 | Q5RDA3 (/ISS) Q8BIQ5 (/ISS) Q8HXM1 (/ISS) |
|
Cleavage body GO:0071920
A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
|
3 | Q5RDA3 (/ISS) Q8BIQ5 (/ISS) Q8HXM1 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q8BIQ5 (/ISO) Q8C7E9 (/ISO) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q9H0L4 (/IDA) |
|
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
|
1 | Q8BIQ5 (/ISO) |
|
MRNA cleavage stimulating factor complex GO:0005848
A protein complex required for mRNA cleavage but not for poly(A) addition.
|
1 | Q9VE52 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q8BIQ5 (/ISO) |
|
Cleavage body GO:0071920
A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
|
1 | Q8BIQ5 (/ISO) |
