The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 231: Cleavage and polyadenylation specificity factor su...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
10 Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI) Q8N684 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
10 Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS)
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
10 Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
10 Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS)
Protein tetramerization GO:0051262
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
Pre-mRNA cleavage required for polyadenylation GO:0098789
The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
10 Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP)
MRNA alternative polyadenylation GO:0110104
The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
10 Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP) Q8N684 (/IMP)
Messenger ribonucleoprotein complex assembly GO:1990120
The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
Pre-mRNA cleavage required for polyadenylation GO:0098789
The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
MRNA alternative polyadenylation GO:0110104
The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
Messenger ribonucleoprotein complex assembly GO:1990120
The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
Protein tetramerization GO:0051262
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
1 Q8BTV2 (/ISO)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
1 Q8BTV2 (/ISO)
Pre-mRNA cleavage required for polyadenylation GO:0098789
The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
1 Q8BTV2 (/ISO)
MRNA alternative polyadenylation GO:0110104
The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
1 Q8BTV2 (/ISO)
Messenger ribonucleoprotein complex assembly GO:1990120
The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
1 Q8BTV2 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
10 Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS) Q8N684 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
MRNA cleavage factor complex GO:0005849
Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
10 Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA) Q8N684 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
10 Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA) Q8N684 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
MRNA cleavage factor complex GO:0005849
Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
2 Q5XI29 (/ISS) Q8BTV2 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8BTV2 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BTV2 (/ISO)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
1 Q8BTV2 (/ISO)
MRNA cleavage factor complex GO:0005849
Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
1 Q8BTV2 (/ISO)
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