The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 180: Deleted in azoospermia-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 O57437 (/IPI) Q13117 (/IPI) Q64368 (/IPI) Q86SG3 (/IPI) Q86SG3 (/IPI) Q92904 (/IPI) Q92904 (/IPI) Q92904 (/IPI) Q9NQZ3 (/IPI) Q9NQZ3 (/IPI)
(5 more)
Translation activator activity GO:0008494
Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.
12 O57437 (/IDA) Q64368 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA)
(2 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 Q13117 (/TAS) Q92904 (/TAS) Q92904 (/TAS) Q92904 (/TAS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 O57437 (/IDA) Q9YGW7 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
2 Q64368 (/IDA) Q9YGW7 (/IDA)
Translation activator activity GO:0008494
Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q9YGW7 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q64368 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q9YGW7 (/IMP)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of translational initiation GO:0045948
Any process that activates or increases the frequency, rate or extent of translational initiation.
11 O57437 (/IDA) Q64368 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA)
(1 more)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
3 Q92904 (/TAS) Q92904 (/TAS) Q92904 (/TAS)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
2 O57437 (/IMP) Q64368 (/IMP)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
Positive regulation of translational initiation GO:0045948
Any process that activates or increases the frequency, rate or extent of translational initiation.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
1 Q64368 (/IMP)
Female meiosis II GO:0007147
The cell cycle process in which the second meiotic division occurs in the female germline.
1 Q64368 (/IMP)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
1 Q13117 (/TAS)
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
1 O57437 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9YGW7 (/IDA)
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
1 Q64368 (/IMP)
Negative regulation of gene silencing by miRNA GO:0060965
Any process that decreases the rate, frequency, or extent of gene silencing by miRNA.
1 Q9YGW7 (/IDA)
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q9YGW7 (/IDA)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
13 Q13117 (/IDA) Q86SG3 (/IDA) Q86SG3 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q92904 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 O57437 (/IDA) Q64368 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9YGW7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q64368 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA) Q9NQZ3 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q92904 (/TAS) Q92904 (/TAS) Q92904 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
Mitochondrial cloud GO:0032019
A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
2 Q4V7Y4 (/ISS) Q76CY5 (/ISS)
Pole plasm GO:0045495
Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
2 O57437 (/IDA) Q76CY5 (/IDA)
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
1 Q64368 (/IDA)
Mitochondrial cloud GO:0032019
A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
1 O57437 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q64368 (/ISO)
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