The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 131: Heterogeneous nuclear ribonucleoprotein h3 isoform

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
44 P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI) P31942 (/IPI)
(34 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
42 P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA) P31942 (/HDA)
(32 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
42 P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS)
(32 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
41 P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS)
(31 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 Q8IG99 (/ISS) Q9VGH5 (/ISS)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q12849 (/TAS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
41 P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS)
(31 more)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
41 P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS)
(31 more)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
41 P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS)
(31 more)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
41 P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP) P31942 (/IEP)
(31 more)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
Maternal specification of dorsal/ventral axis, oocyte, germ-line encoded GO:0007311
Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
Pole plasm oskar mRNA localization GO:0045451
Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
Chromosome organization GO:0051276
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
Intracellular mRNA localization involved in pattern specification process GO:0060810
Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.
2 Q8IG99 (/IMP) Q9VGH5 (/IMP)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
1 Q12849 (/TAS)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
1 Q8C5Q4 (/IMP)
Morphogenesis of embryonic epithelium GO:0016331
The process in which the anatomical structures of embryonic epithelia are generated and organized.
1 Q8C5Q4 (/IMP)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
82 A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA) A0A024QZK8 (/IDA)
(72 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
41 P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA) P31942 (/IDA)
(31 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
41 P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS)
(31 more)
Spliceosomal complex GO:0005681
Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
41 P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS) P31942 (/NAS)
(31 more)
Spliceosomal complex GO:0005681
Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
41 P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS) P31942 (/TAS)
(31 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 A0A024RD99 (/IDA) A0A024RD99 (/IDA) F5H5I6 (/IDA) H0Y8R1 (/IDA) H0YAK1 (/IDA) Q12849 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 D3YWT1 (/ISO) D3Z3N4 (/ISO) D3Z3N4 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 D3YWT1 (/ISO) D3Z3N4 (/ISO) D3Z3N4 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q8IG99 (/IPI) Q9VGH5 (/IPI)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q12849 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8C5Q4 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8C5Q4 (/ISO)
Ribonucleoprotein granule GO:0035770
A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
1 Q12849 (/IDA)
Ribonucleoprotein granule GO:0035770
A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
1 Q8C5Q4 (/ISO)
Ribonucleoprotein granule GO:0035770
A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
1 Q8C5Q4 (/ISS)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
1 Q12849 (/IDA)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
1 Q8C5Q4 (/ISO)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
1 Q8C5Q4 (/ISS)
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