The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Nucleotide cyclase
".
FunFam 12: Adenylate cyclase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
|
3 | F1LQT1 (/IDA) P51828 (/IDA) P51829 (/IDA) |
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
|
2 | P51828 (/IMP) P51829 (/IMP) |
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
|
1 | P51829 (/ISO) |
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
|
1 | Q29450 (/ISS) |
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
|
1 | P51829 (/TAS) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of adaptive immune response GO:0002819
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
|
2 | P51828 (/ISS) Q29450 (/ISS) |
CAMP biosynthetic process GO:0006171
The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
|
2 | F1LQT1 (/IDA) P51828 (/IDA) |
Activation of adenylate cyclase activity GO:0007190
Any process that initiates the activity of the inactive enzyme adenylate cyclase.
|
2 | P51828 (/TAS) P51829 (/TAS) |
Cellular response to lithium ion GO:0071285
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
|
2 | P51828 (/ISS) Q29450 (/ISS) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
2 | P51829 (/ISS) Q29450 (/ISS) |
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
|
2 | P51828 (/ISS) Q29450 (/ISS) |
Regulation of adaptive immune response GO:0002819
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
|
1 | P51829 (/IMP) |
Renal water homeostasis GO:0003091
Renal process involved in the maintenance of an internal steady state of water in the body.
|
1 | P51828 (/TAS) |
CAMP biosynthetic process GO:0006171
The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
|
1 | P51829 (/ISO) |
CAMP biosynthetic process GO:0006171
The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
|
1 | P51829 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | F1LQT1 (/NAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | P51828 (/TAS) |
Adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).
|
1 | F1LQT1 (/IMP) |
Adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).
|
1 | P51829 (/ISO) |
Adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).
|
1 | P51828 (/TAS) |
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
|
1 | P51828 (/TAS) |
Activation of protein kinase A activity GO:0034199
Any process that initiates the activity of the inactive enzyme protein kinase A.
|
1 | P51828 (/TAS) |
Maternal process involved in female pregnancy GO:0060135
A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.
|
1 | F1LQT1 (/IEP) |
Cellular response to lithium ion GO:0071285
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
|
1 | P51829 (/IDA) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
1 | P51828 (/IDA) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
1 | P51829 (/ISO) |
Cellular response to glucagon stimulus GO:0071377
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
|
1 | P51828 (/TAS) |
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
|
1 | P51829 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P51828 (/TAS) P51829 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q29450 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P51828 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | F1LQT1 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P51829 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P51828 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P51829 (/ISO) |