The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histidine kinase-like ATPase, C-terminal domain
".
FunFam 91: Sensor histidine kinase/response regulator EvgS
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
9 | P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) |
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
9 | P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) |
|
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
|
9 | P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
9 | P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) |
|
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
9 | P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) P30855 (/IMP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
9 | P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) P30855 (/IDA) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
9 | P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) P30855 (/RCA) |
