The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histidine kinase-like ATPase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Molecular chaperone HtpG

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
105 P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI)
(95 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
105 P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA)
(95 more)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
105 P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA)
(95 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
105 P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI) P0A6Z3 (/IPI)
(95 more)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
1 Q386P5 (/ISA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
105 P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP) P0A6Z3 (/EXP)
(95 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
105 P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP)
(95 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
105 P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP) P0A6Z3 (/IEP)
(95 more)
Cellular response to superoxide GO:0071451
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
9 P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP) P9WMJ7 (/IEP)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
4 P22359 (/ISS) P22359 (/ISS) P22359 (/ISS) P22359 (/ISS)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
1 Q386P5 (/ISM)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
1 Q86L04 (/IMP)
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
1 Q86L04 (/IMP)
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
1 Q86L04 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
108 P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA) P0A6Z3 (/IDA)
(98 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
105 P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA) P0A6Z3 (/HDA)
(95 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
9 P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
9 P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA) P9WMJ7 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 P42555 (/IDA) P42555 (/IDA) P42555 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q86L04 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q386P5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q386P5 (/ISM)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q386P5 (/RCA)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
1 Q386P5 (/IDA)
Spore wall GO:0031160
The specialized envelope lying outside the cell membrane of a spore.
1 Q86L04 (/NAS)
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