The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histidine kinase-like ATPase, C-terminal domain
".
FunFam 42: Two-component sensor histidine kinase KdpD
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
13 |
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
(3 more) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
13 |
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
P21865 (/IPI)
(3 more) |
|
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
1 | Q605R4 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | E0X9C7 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Detection of chemical stimulus GO:0009593
The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Cellular response to extracellular stimulus GO:0031668
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
1 | Q605R4 (/ISS) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q605R4 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
13 |
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
P21865 (/IDA)
(3 more) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
13 |
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
P21865 (/ISM)
(3 more) |
