The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histidine kinase-like ATPase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: PAS domain-containing sensor histidine kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
18 A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS)
(8 more)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
12 A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS)
(2 more)
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
1 Q7CY45 (/TAS)
Red or far-red light photoreceptor activity GO:0009883
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.
1 Q7CY45 (/TAS)
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
1 B9UP04 (/IMP)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
18 A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS)
(8 more)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
12 A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS) A0A0F7RB54 (/ISS)
(2 more)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
2 A0A0F7RJZ7 (/ISS) A0A0F7RJZ7 (/ISS)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
2 A0A0F7RJZ7 (/ISS) A0A0F7RJZ7 (/ISS)
Red, far-red light phototransduction GO:0009585
The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
1 Q7CY45 (/TAS)
Protein-chromophore linkage via peptidyl-cysteine GO:0019922
The covalent linking of a chromophore to a protein via peptidyl-cysteines.
1 Q7CY45 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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