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CATH Superfamily 3.30.56.50

Putative DNA-binding domain, N-terminal subdomain of bacterial translation initiation factor IF2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Putative DNA-binding domain, N-terminal subdomain of bacterial translation initiation factor IF2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Translation initiation factor IF-2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 116 P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI) P0A705 (/IPI)
(106 more)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
Guanosine tetraphosphate binding GO:0097216
Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
 7 Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
 7 Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS) Q9KU80 (/ISS)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
 6 Q9HV55 (/IMP) Q9HV55 (/IMP) Q9HV55 (/IMP) Q9HV55 (/IMP) Q9HV55 (/IMP) Q9HV55 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 116 P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA) P0A705 (/IDA)
(106 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 116 P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA) P0A705 (/HDA)
(106 more)