The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Chloramphenicol acetyltransferase-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Tryptamine hydroxycinnamoyl transferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Omega-hydroxypalmitate O-feruloyl transferase. [EC: 2.3.1.188]
Feruloyl-CoA + 16-hydroxypalmitate = CoA + 16-feruloyloxypalmitate.
  • p-coumaroyl-CoA and sinapoyl-CoA also act as substrates.
  • The enzyme is widely distributed in roots of higher plants.
4 A0A178UGL4 A0A178UGL4 Q94CD1 Q94CD1
Agmatine N(4)-coumaroyltransferase. [EC: 2.3.1.64]
4-coumaroyl-CoA + agmatine = CoA + N-(4-guanidinobutyl)-4- hydroxycinnamamide.
    2 A9ZPJ6 A9ZPJ7
    Rosmarinate synthase. [EC: 2.3.1.140]
    Caffeoyl-CoA + (R)-3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.
    • Involved with EC 1.1.1.237 in the biosynthesis of rosmarinic acid.
    • Characterized from the plant Melissa officinalis L. (lemon balm).
    2 A0PDV5 G0LD36
    Shikimate O-hydroxycinnamoyltransferase. [EC: 2.3.1.133]
    4-coumaroyl-CoA + shikimate = CoA + 4-coumaroylshikimate.
    • Caffeoyl-CoA, feruloyl-CoA and sinapoyl-CoA can also act as donors, more slowly.
    1 Q9FI78
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