The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Chloramphenicol acetyltransferase-like domain
".
FunFam 4: Acetyltransferase component of pyruvate dehydrogen...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dihydrolipoyllysine-residue acetyltransferase activity GO:0004742
Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.
|
61 |
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
(51 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
61 |
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
P06959 (/IPI)
(51 more) |
|
Lipoic acid binding GO:0031405
Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid.
|
61 |
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
(51 more) |
|
Dihydrolipoyllysine-residue acetyltransferase activity GO:0004742
Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.
|
2 | Q9KPF5 (/ISS) Q9KPF5 (/ISS) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetyl-CoA biosynthetic process from pyruvate GO:0006086
The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
|
61 |
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
(51 more) |
|
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
|
61 |
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
P06959 (/IMP)
(51 more) |
|
Acetyl-CoA biosynthetic process from pyruvate GO:0006086
The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
|
3 | Q86AD5 (/ISS) Q9KPF5 (/ISS) Q9KPF5 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
61 |
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
P06959 (/HDA)
(51 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
61 |
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
(51 more) |
|
Pyruvate dehydrogenase complex GO:0045254
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
|
61 |
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
P06959 (/IDA)
(51 more) |
|
Pyruvate dehydrogenase complex GO:0045254
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
|
61 |
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
P06959 (/IGI)
(51 more) |
|
Cytosolic pyruvate dehydrogenase complex GO:0045250
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.
|
2 | Q9KPF5 (/ISS) Q9KPF5 (/ISS) |
|
Pyruvate dehydrogenase complex GO:0045254
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
|
1 | Q86AD5 (/ISS) |