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CATH Superfamily 3.30.54.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Alanine--tRNA ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
 47 A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA) A7ZQC5 (/IDA)
(37 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Aminoacyl-tRNA editing activity GO:0002161
The hydrolysis of an incorrectly aminoacylated tRNA.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Aminoacyl-tRNA editing activity GO:0002161
The hydrolysis of an incorrectly aminoacylated tRNA.
 17 P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP) P00957 (/IMP)
(7 more)
Ser-tRNA(Ala) hydrolase activity GO:0002196
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 17 P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI) P00957 (/IPI)
(7 more)
Alanine-tRNA ligase activity GO:0004813
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
 6 Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Alanyl-tRNA aminoacylation GO:0006419
The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
 6 Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS) Q56648 (/ISS)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
 2 Q9FFC7 (/IMP) Q9FFC7 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 23 P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA)
(13 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 17 P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA) P00957 (/IDA)
(7 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 17 P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA) P00957 (/HDA)
(7 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
 6 P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 6 P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA) P9WFW7 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
 2 Q9FFC7 (/IDA) Q9FFC7 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
 2 Q9FFC7 (/IDA) Q9FFC7 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
 2 Q9FFC7 (/IDA) Q9FFC7 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 2 Q9FFC7 (/IDA) Q9FFC7 (/IDA)
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