The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: stAR-related lipid transfer protein 3 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q14849 (/IPI) Q14849 (/IPI)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
2 Q14849 (/IDA) Q14849 (/IDA)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
2 Q61542 (/ISO) Q61542 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q14849 (/IDA) Q14849 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q61542 (/ISO) Q61542 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Vesicle tethering to endoplasmic reticulum GO:0099044
The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
2 Q14849 (/TAS) Q14849 (/TAS)
C21-steroid hormone biosynthetic process GO:0006700
The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
2 Q14849 (/TAS) Q14849 (/TAS)
Progesterone biosynthetic process GO:0006701
The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
2 Q61542 (/IMP) Q61542 (/IMP)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
2 Q14849 (/TAS) Q14849 (/TAS)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
2 Q14849 (/TAS) Q14849 (/TAS)
Cholesterol metabolic process GO:0008203
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
2 Q14849 (/TAS) Q14849 (/TAS)
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q14849 (/IDA) Q14849 (/IDA)
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q61542 (/ISO) Q61542 (/ISO)
Vesicle tethering to endoplasmic reticulum GO:0099044
The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
2 Q14849 (/IDA) Q14849 (/IDA)
Vesicle tethering to endoplasmic reticulum GO:0099044
The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
2 Q61542 (/ISO) Q61542 (/ISO)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum-endosome membrane contact site GO:0140284
A contact site between the endoplasmic reticulum membrane and the endosome membrane.
5 F7B909 (/ISS) Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
4 Q61542 (/ISS) Q61542 (/ISS) Q90ZB9 (/ISS) Q9DFS4 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q61542 (/ISS) Q61542 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q14849 (/TAS) Q14849 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q61542 (/IDA) Q61542 (/IDA)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
2 Q14849 (/HDA) Q14849 (/HDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
2 Q61542 (/IDA) Q61542 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2 Q61542 (/TAS) Q61542 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q14849 (/TAS) Q14849 (/TAS)
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
2 Q14849 (/IDA) Q14849 (/IDA)
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
2 Q61542 (/ISO) Q61542 (/ISO)
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
2 Q14849 (/IDA) Q14849 (/IDA)
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
2 Q61542 (/ISO) Q61542 (/ISO)
Endoplasmic reticulum-endosome membrane contact site GO:0140284
A contact site between the endoplasmic reticulum membrane and the endosome membrane.
2 Q14849 (/IDA) Q14849 (/IDA)
Endoplasmic reticulum-endosome membrane contact site GO:0140284
A contact site between the endoplasmic reticulum membrane and the endosome membrane.
2 Q61542 (/ISO) Q61542 (/ISO)
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