The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Phosphatidylinositol transfer protein membrane ass...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
4 O00562 (/IDA) O00562 (/IDA) P43125 (/IDA) Q9BZ72 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
3 O00562 (/IDA) O00562 (/IDA) Q9BZ72 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 O00562 (/IPI) O00562 (/IPI) Q6ZPQ6 (/IPI)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
3 O00562 (/IMP) O00562 (/IMP) Q9BZ72 (/IMP)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
3 O00562 (/IDA) O00562 (/IDA) P43125 (/IDA)
Phosphatidic acid binding GO:0070300
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
3 O00562 (/IDA) O00562 (/IDA) P43125 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 O35954 (/ISO) Q6ZPQ6 (/ISO)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2 O35954 (/ISA) Q6ZPQ6 (/ISA)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
2 O35954 (/ISO) Q6ZPQ6 (/ISO)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
2 O00562 (/TAS) O00562 (/TAS)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
2 O35954 (/ISO) Q6ZPQ6 (/ISO)
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
2 O00562 (/IDA) O00562 (/IDA)
Calcium transmembrane transporter activity, phosphorylative mechanism GO:0005388
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
1 P43125 (/ISS)
Phosphatidylcholine transporter activity GO:0008525
Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 P43125 (/IDA)
Phosphatidylinositol transfer activity GO:0008526
Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
1 P43125 (/NAS)
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
1 O35954 (/ISO)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 O35954 (/ISO)
Phosphatidic acid binding GO:0070300
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
1 O35954 (/ISO)
Phosphatidic acid transfer activity GO:1990050
Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.
1 P43125 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylinositol biosynthetic process GO:0006661
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
3 O00562 (/TAS) O00562 (/TAS) Q9BZ72 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
3 O00562 (/TAS) O00562 (/TAS) P43125 (/TAS)
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
3 O00562 (/IDA) O00562 (/IDA) P43125 (/IDA)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
2 O00562 (/NAS) O00562 (/NAS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 O00562 (/TAS) O00562 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 P43125 (/IMP)
Phototransduction, visible light GO:0007603
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 P43125 (/IMP)
Sensory perception of smell GO:0007608
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
1 P43125 (/IMP)
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
1 O35954 (/ISO)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
1 P43125 (/IMP)
Deactivation of rhodopsin mediated signaling GO:0016059
The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
1 P43125 (/IMP)
Deactivation of rhodopsin mediated signaling GO:0016059
The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
1 P43125 (/TAS)
Phosphatidylinositol metabolic process GO:0046488
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
1 P43125 (/IMP)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 Q9BZ72 (/IDA)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 Q6ZPQ6 (/ISO)
Cellular response to light stimulus GO:0071482
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 P43125 (/IMP)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
4 A0A024R5I7 (/IDA) A0A024R5I7 (/IDA) O00562 (/IDA) O00562 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 A0A024R5I7 (/IDA) A0A024R5I7 (/IDA) O00562 (/IDA) O00562 (/IDA)
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
4 A0A024R5I7 (/IDA) A0A024R5I7 (/IDA) O00562 (/IDA) O00562 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O00562 (/TAS) O00562 (/TAS) Q9BZ72 (/TAS)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
3 O00562 (/ISS) O00562 (/ISS) O35954 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 O00562 (/TAS) O00562 (/TAS)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
2 F1LXD6 (/IDA) Q5U2N3 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
2 O35954 (/ISO) Q6ZPQ6 (/ISO)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
1 O35954 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O35954 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P43125 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P43125 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P43125 (/TAS)
Subrhabdomeral cisterna GO:0016029
A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.
1 P43125 (/NAS)
Subrhabdomeral cisterna GO:0016029
A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.
1 P43125 (/TAS)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
1 G5EED9 (/IDA)
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
1 O35954 (/ISO)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 G5EED9 (/IDA)
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