The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MHC class I-like antigen recognition-like
".
FunFam 37:
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
2 | A0A1W2P7M5 (/IPI) Q330P3 (/IPI) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of immune response to tumor cell GO:0002839
Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Natural killer cell activation GO:0030101
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
|
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Positive regulation of natural killer cell activation GO:0032816
Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Natural killer cell mediated cytotoxicity GO:0042267
The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
|
Susceptibility to natural killer cell mediated cytotoxicity GO:0042271
The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Positive regulation of macrophage activation GO:0043032
Any process that stimulates, induces or increases the rate of macrophage activation.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | A0A1W2P7M5 (/IDA) Q330P3 (/IDA) |
|
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
2 | A0A1W2P7M5 (/ISO) Q330P3 (/ISO) |