The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aconitase, domain 3
".
FunFam 8: Aconitate hydratase B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
50 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(40 more) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
50 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(40 more) |
|
Aconitate hydratase activity GO:0003994
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
|
50 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(40 more) |
|
2-methylisocitrate dehydratase activity GO:0047456
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O.
|
50 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(40 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
42 |
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
P36683 (/IPI)
(32 more) |
|
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
42 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(32 more) |
|
Aconitate hydratase activity GO:0003994
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
|
25 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(15 more) |
|
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
24 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q8ZRS8 (/ISS)
Q8ZRS8 (/ISS)
Q8ZRS8 (/ISS)
Q8ZRS8 (/ISS)
Q8ZRS8 (/ISS)
Q8ZRS8 (/ISS)
(14 more) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
16 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(6 more) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
16 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(6 more) |
|
2-methylisocitrate dehydratase activity GO:0047456
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O.
|
16 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(6 more) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glyoxylate cycle GO:0006097
A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
|
42 |
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
(32 more) |
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
42 |
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
P36683 (/NAS)
(32 more) |
|
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
42 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(32 more) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
42 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(32 more) |
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
25 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(15 more) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
16 |
P56418 (/ISS)
P56418 (/ISS)
P74582 (/ISS)
P74582 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
Q9I2V5 (/ISS)
(6 more) |
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
8 | Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
8 | Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) Q8ZRS8 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
42 |
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
P36683 (/IDA)
(32 more) |