View in Gene3D

CATH Superfamily 3.30.499.10

Aconitase, domain 3

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aconitase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 7: 3-isopropylmalate dehydratase large subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-isopropylmalate dehydratase. [EC: 4.2.1.33]
(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
  • Forms part of the leucine-biosynthesis pathway.
  • Brings about the interconversion of the two isomers of isopropylmalate.
 17300 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49 A0A023YS49
(17290 more...)
Dimethylmaleate hydratase. [EC: 4.2.1.85]
(2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.
  • Inhibited by oxygen.
  • Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri.
  • Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.1.3.32.
 4 A0A1H3FX95 A0A1H3FX95 Q0QLE2 Q0QLE2