The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aconitase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Homoaconitase, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
2 P49367 (/ISA) P49367 (/ISA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P49367 (/IPI) P49367 (/IPI)
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
1 Q92412 (/IDA)
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
1 Q92412 (/IMP)
Homoaconitate hydratase activity GO:0004409
Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
1 Q9UT74 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysine biosynthetic process via aminoadipic acid GO:0019878
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
4 P49367 (/IMP) P49367 (/IMP) Q92412 (/IMP) Q9UT74 (/IMP)
Lysine biosynthetic process GO:0009085
The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
3 Q4WUL6 (/IMP) Q5A644 (/IMP) Q9UT74 (/IMP)
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
1 Q9UT74 (/NAS)
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
1 Q4WUL6 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P49367 (/HDA) P49367 (/HDA) Q9UT74 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9UT74 (/IMP)