The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA ligase/mRNA capping enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Cap methyltransferase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483
Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.
12 A2VE39 (/ISS) D2HRF1 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5U2Z5 (/ISS) Q6GQ76 (/ISS)
(2 more)
MRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483
Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
MRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483
Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.
1 Q9DBC3 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
12 A2VE39 (/ISS) D2HRF1 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5U2Z5 (/ISS) Q6GQ76 (/ISS)
(2 more)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
12 A2VE39 (/ISS) D2HRF1 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5U2Z5 (/ISS) Q6GQ76 (/ISS)
(2 more)
Cap1 mRNA methylation GO:0097309
Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.
12 A2VE39 (/ISS) D2HRF1 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5U2Z5 (/ISS) Q6GQ76 (/ISS)
(2 more)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 Q8N1G2 (/IMP) Q8N1G2 (/IMP) Q8N1G2 (/IMP) Q8N1G2 (/IMP) Q8N1G2 (/IMP) Q8N1G2 (/IMP)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
Cap1 mRNA methylation GO:0097309
Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
1 Q9DBC3 (/ISO)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
1 Q9DBC3 (/ISO)
Cap1 mRNA methylation GO:0097309
Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.
1 Q9DBC3 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 A2VE39 (/ISS) D2HRF1 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5R981 (/ISS) Q5U2Z5 (/ISS) Q6GQ76 (/ISS)
(2 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA) Q8N1G2 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9DBC3 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9DBC3 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9DBC3 (/ISO)
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