The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"PAS domain
".
FunFam 676: Nuclear receptor coactivator 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
|
1 | Q9EPU2 (/ISS) |
|
RNA polymerase II regulatory region DNA binding GO:0001012
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q9EPU2 (/IDA) |
|
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
|
1 | Q9EPU2 (/IPI) |
|
Nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
|
1 | Q9EPU2 (/IDA) |
|
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
|
1 | Q9EPU2 (/IPI) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q9EPU2 (/IMP) |
|
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | Q9EPU2 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | Q9EPU2 (/IEP) |
|
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
1 | Q9EPU2 (/IMP) |
|
Positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145
Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
|
1 | Q9EPU2 (/IMP) |
|
Positive regulation of intracellular estrogen receptor signaling pathway GO:0033148
Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
1 | Q9EPU2 (/IDA) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9EPU2 (/IMP) |
|
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
|
1 | Q9EPU2 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9EPU2 (/IMP) |
|
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | Q9EPU2 (/IDA) |
|
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
|
1 | Q9EPU2 (/ISS) |
|
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
|
1 | Q9EPU2 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9EPU2 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9EPU2 (/IDA) |
|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q9EPU2 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9EPU2 (/IDA) |