The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: GTR1p Cytoplasmic GTPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
9 Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 O74824 (/ISM)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Transcription by RNA polymerase I GO:0006360
The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Transcription by RNA polymerase I GO:0006360
The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
9 Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
9 Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI)
Phosphate ion transport GO:0006817
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
9 Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI)
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Protein localization to vacuolar membrane GO:1903778
A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
9 Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI) Q00582 (/IGI)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
9 Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP) Q00582 (/IMP)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
2 A0A1D8PI64 (/IMP) O74824 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
1 O74824 (/NAS)
Regulation of single-species biofilm formation on inanimate substrate GO:1900231
Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1 A0A1D8PI64 (/IMP)
Negative regulation of TORC1 signaling GO:1904262
Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
1 O74824 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
10 O74824 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Gtr1-Gtr2 GTPase complex GO:1990131
A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.
10 O74824 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI) Q00582 (/IPI)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
9 Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA) Q00582 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
EGO complex GO:0034448
A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p.
9 Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA) Q00582 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O74824 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O74824 (/HDA)
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