The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HIT-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: m7GpppX diphosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q12123 (/IPI) Q12123 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
RNA 7-methylguanosine cap binding GO:0000340
Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
8 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA)
Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides GO:0016818
Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
8 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA)
Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides GO:0016818
Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
8 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
8 Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI) Q06151 (/IPI)
Exoribonuclease activator activity GO:0044692
Binds to and increases the activity of an exoribonuclease.
8 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA)
M7G(5')pppN diphosphatase activity GO:0050072
Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide.
8 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA)
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
2 Q12123 (/IDA) Q12123 (/IDA)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
10 Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q12123 (/IGI) Q12123 (/IGI)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Regulation of cell aging GO:0090342
Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
10 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q12123 (/IMP) Q12123 (/IMP)
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
8 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP)
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
8 Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS) Q06151 (/TAS)
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
8 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
8 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP)
Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay GO:0031086
A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
8 Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI) Q06151 (/IGI)
Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay GO:0031086
A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
8 Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP) Q06151 (/IMP)
Positive regulation of exoribonuclease activity GO:1901919
Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.
8 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA)
Cellular response to nutrient GO:0031670
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
2 Q12123 (/IDA) Q12123 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q12123 (/HDA) Q12123 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
10 Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q06151 (/IDA) Q12123 (/IDA) Q12123 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA) Q06151 (/HDA)
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